In a midterm election year already chock full of change, Republican Speaker of the House Paul Ryan鈥檚 announcement on Wednesday that he is not seeking re-election is sending shock waves through Washington, leaving the GOP in an uphill battle to maintain control of Congress.

鈥淵ou realize something when you take this job,鈥 Ryan said on Wednesday morning. 鈥淚t鈥檚 a big job with a lot riding on you 鈥 but you also know this is not a job that does not last forever. 鈥 You realize you hold the office for just a small part of our history. So you better make the most of it.鈥

Ryan cited wanting to stay home with his family as a key reason for his decision not to seek re-election, and his announcement suggests how troubled the GOP actually is. In total, 25 Republican members of the House and three senators have now announced their retirement, leaving the GOP open for massive losses in November in light of the fact that it has been historically easier to flip a seat from one party to another when an incumbent retires.

Ryan鈥檚 departure is also adding another layer to this year鈥檚 midterm elections by forcing the GOP into a leadership race 鈥 an unwelcome distraction for his party. Although House Majority Leader Kevin McCarthy and House Majority Whip Steve Scalise of Louisiana may both seek Ryan鈥檚 position as Speaker as the GOP works to elect a new rep for the House, the Republican party could suffer losses by ignoring key races 鈥 likely including Ryan鈥檚 own seat. (The current longshot Republican candidate to fill that seat is a prominent white nationalist.)

Analysts agree that Ryan鈥檚 departure signals a lack of internal trust in the GOP as a whole, with insiders calling his departure a 鈥渢ectonic shift鈥 for the party. 鈥淭his is going to make every Republican donor believe the House can鈥檛 be held,鈥 the unnamed source toldAxios.

Although we won鈥檛 know just how damaging Ryan鈥檚 retirement could be for his party until election day, his decision to retire in a midterm year rife with challenges speaks to the greater issues facing the Republicans in 2018.

(Photo via Mark Wilson/Getty)