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Raise your hand if one of your biggest New Year's resolutions for 2026 is to maintain a higher-quality skincare routine. Yep, same here. *Raises both hands high.*
As someone who spent most of my life sifting through cheap drugstore products for my acne flare-ups, I finally decided to switch gears to Korean skincare to see true, lasting results.
Unfortunately, my quest over the past six months to achieve perfect glass skin has backfired, as I’ve ended up mixing chemicals and ingredients in my various skin products that definitely shouldn't be combined. It seems like my skin has been having some sort of allergic reaction, since I’m noticing blotchy red flare-ups all over my face that refuse to go away.
The good news, though, is that this is exactly what PDRN (an acronym for polydeoxyribonucleotides) skincare targets: sensitive, damaged skin. So if you’re also looking to repair inflammation or damage, PDRN skincare has you covered! Additionally, it adds an ethereal glow to your face, with that ever-desirable glass skin effect. What more could you ask for in a single product?
Let’s narrow down the best PDRN skincare products on the market so that we all can enter 2026 with the most lovely skin possible.
Amazon
Anua PDRN Hyaluronic Acid Capsule 100 Serum
Anyone here cursed with dreaded dry skin? It’s Flake City on my face right now, which unfortunately leads to visible signs of aging. Skin that lacks hydration appears more haggard and wrinkled, but this little product right here will moisturize you back into a supple state of plumpness and overall skin health.
Amazon
VT Cosmetics PDRN 100 Essence
If your main concern is avoiding animal products in your skincare, this is the perfect plant-based alternative. While most other PDRN skincare products are fish-derived, this one is sourced from the herbal root, ginseng.
Amazon
Medicube PDRN Pink Peptide Serum
This magic-in-a-bottle is so effective and praised by skincare enthusiasts that you’d never believe it’s only $15 (was $22). Wish to hydrate your skin? Check. Care to add firmness? Check. Need something fit for sensitive skin? Check, check, check.
Amazon
Rejuran Turnover Ampoule
If you really want to invest in a top-tier PDRN skincare formula for repair and glow, Rejuran's Turnover Ampoule formulated with c-PDRN is going to be your new best friend. It’s perfect for repairing damaged skin and is made by the company behind one of South Korea’s most popular injectable facials.
Amazon
Genabelle PDRN Vita Toning Ampoule
Does anyone else feel like their skin will be inflamed after coating it with even the simplest ingredients? If your skin tends to flare up over just about anything, the Genabelle PDRN Vita Toning Ampoule will be great for you. It’s meant to treat sensitive skin while offering the same effective results as other PDRN skincare products.
Amazon
IOPE BIO-PDRN Caffeine Shot Serum
If your main issue is sagging skin, this brilliant product is a miracle-worker. This option is also plant-based, using green tea, caffeine, and niacinamide.
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