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The 6 Best Prime Video Shows To Watch This May

As we step into May, a fresh batch of series is hitting Amazon Prime Video, and there's something for every kind of viewer. Whether you're into heartfelt comedy, drama, or even cartoons, this month's lineup will give you plenty of reasons to stay in a stream.
So, here's every show you can expect (and plan to binge) on Prime Video this May.
Scroll to see all the Prime Video shows you should watch in May 2025!
Prime Video
1. Octopus! – May 8
Phoebe Waller-Bridge narrates Octopus!, a stunning two-part documentary special that drops on Prime Video on May 8 and dives into the world of the Giant Pacific Octopus.
The series is set to include interviews with scientists, divers, and even comedian Tracy Morgan while showcasing the intelligence and adaptability of these creatures. Wildlife fans won't want to miss Octopus!, which is beautifully shot and perfect for fans of nature docs with a personal touch.
Prime Video
2. Overcompensating – May 15
Created by internet personality Benito Skinner, Overcompensating is a coming-of-age college comedy that's full of chaotic self-discovery.
Benito actually plays Benny, an ex-football star and former homecoming king who's struggling to accept his sexuality and navigate life beyond the locker room. He teams up with Carmen, another outsider who wants to reinvent herself, and together, they dive into wild parties, awkward hookups, and emotional growing pains.
Overcompensating mixes outrageous humor with genuine vulnerability. You can catch it on Prime Video on May 15.
Prime Video
3. Motorheads – May 20
Set in the gritty Rust Belt town of Ironwood, Pennsylvania, Motorheads is a coming-of-age drama that will definitely rev up some emotion. The series follows a group of high school misfits who find escape and purpose through their shared obsession with street racing.
And as the gang navigates the trials and tribulations of teenage life (like first loves), they also confront their own demons. You can stream this show starting May 20 on Prime Video.
Prime Video
4. Clarkson's Farm (Season 4) – May 23
Jeremy Clarkson is returning to the unpredictable world of agriculture in the latest season of Clarkson's Farm. With Kaleb off touring the country, Jeremy is left to manage the farm solo, which could spell trouble for the crops.
You can look forward to more farming disasters, unexpected weather, and unfiltered humor as Jeremy attempts to keep his side project afloat. Stream Season 4 of this show beginning on May 23.
Prime Video
5. The Second Best Hospital in the Galaxy – May 27
If you're a fan of sci-fi animation, you must check out The Second Best Hospital in the Galaxy. This comedy follows a team of alien doctors who juggle absurd medical emergencies and cosmic mishaps.
With a voice cast that includes Stephanie Hsu, Kieran Culkin, Keke Palmer, and Maya Rudolph, the show's humor is reminiscent of Futurama or Solar Opposites. Stream it starting May 27 on Prime Video.
Prime Video
6. The Better Sister – May 29
Jessica Biel and Elizabeth Banks star in The Better Sister, a psychological thriller that explores the secrets buried beneath family ties.
When Chloe, played by Jessica, finds out her husband Adam is murdered, her strained relationship with her sister Nicky, portrayed by Elizabeth, is put under pressure.
One is a successful media exec, and the other is a recovering addict. Yet, they're forced to reconnect amidst the tragedy and confront their past to get answers about Adam's death. The Better Sister will be available to binge starting May 29.
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