Grey’s Anatomy’s Best Guest Stars Ever

As the longest-running scripted primetime show currently on ABC, Grey's Anatomy has given us a lot in its 13 seasons (and counting) — one of the best TV couples in Meredith and Derek (not to mention the show's real love story between Meredith and Cristina!), a classic spinoff in Private Practice (and another promising firefighter-focused one in the works), and a seemingly endless supply of heart-pounding drama. It has also given us one of our favorite ensemble casts on TV — not to mention some high-grade guest stars. Take a look at some of the celebrities who've checked into Grey Sloan Memorial (formerly Seattle Grace and then Seattle Grace-Mercy West) over the last decade-plus. Fair warning: Some photos may depict graphic medical situations. (Photos via Ron Tom/ABC via Getty + Mitch Haddad/ABC via Getty + Danny Feld/ABC via Getty + Peter "Hopper" Stone/ABC via Getty)